US-Cleared
Self-affirmed GRAS for both live and pasteurized forms, plus completed FDA NDI Notification #1468 for the pasteurized form.
Akkermansia muciniphila · CGMCC No.20955
The Akkermansia You Can Build On
US-cleared · 7 clinical studies & 13 peer-reviewed publications, anchored by a landmark 8-week RCT (P < 0.001) · live & pasteurized.
AKK PROBIO® (Akkermansia muciniphila, CGMCC No.20955) is the Akkermansia ingredient formulators can build on: self-affirmed GRAS for both forms, completed FDA NDI Notification #1468 for the pasteurized form, a deep clinical base, and both live and pasteurized forms.
For R&D
For Regulatory
For QA
For Brand Owners
For Distributors
200+strains screened
18invention patents
13peer-reviewed publications
7clinical studies
GRASself-affirmed, live + pasteurized
FDA NDI#1468, pasteurized form
B2B ingredient positioning
A rare combination for formulators and brand owners
Akkermansia muciniphila is one of the most researched next-generation probiotics, but for a brand, the hard part is launching it. AKK PROBIO® reduces that evaluation burden with self-affirmed GRAS for both forms, completed FDA NDI Notification #1468 for the pasteurized form, 7 clinical studies, 13 peer-reviewed publications, and both live and pasteurized forms.
Three brand pillars
Built for technical review, not retail hype
Clinically Studied
13 peer-reviewed publications and 7 clinical studies, anchored by a landmark 8-week double-blind, placebo-controlled RCT.
Dual-Form
Live probiotic and pasteurized postbiotic forms help teams match the ingredient to supplements, foods, beverages, and other formats.
Regulatory & Safety
Self-affirmed GRAS + FDA NDI #1468
AKK PROBIO® holds self-affirmed GRAS under 21 CFR §170.30 for live and pasteurized forms, and has completed FDA New Dietary Ingredient Notification #1468 for the pasteurized form.
Applications
Live and pasteurized forms for multiple B2B formats
Dietary supplements
Capsules, powders, and gummies, with live or pasteurized positioning.
Food & beverage
Pasteurized form for processing tolerance and shelf-stable formulation.
Sports nutrition
Fits body-composition, metabolic, and recovery-oriented concepts.
Pet health
A documented, safety-evaluated ingredient route for companion-animal gut health.
Science & Evidence
13 publications and 7 clinical studies on the AKK PROBIO strain
Human, safety, and preclinical research support a stronger technical conversation with R&D, QA, and regulatory teams.
Review the evidenceEvaluating Akkermansia for your next formulation?
Request a sample, or talk to our technical team about your application.
AKK PROBIO
CGMCC No.20955
WORLD'S BEST AKKERMANSIA MUCINIPHILA
Akkermansia muciniphila (AKK), a resident gut microbe, colonizes the intestinal mucosal layer. It interacts with immune cells via short-chain fatty acids to exert health-protective effects.In 2019, THANKCOME selected AKK PROBIO from 200 AKK strains. Its preservation number is CGMCC No.20955 (certified by the China General Microbiological Culture Collection Center).Over 3,000 global studies confirm AKK significant potential in intestinal barrier protection, weight management, anti-aging, and anti-inflammation, with broad application prospects.
Protection Of The Intestinal Barrier
Preserves intestinal homeostasis and ameliorates colitis
Weight
Management
Attenuates obesity via gut microbiota-SCFA-GLP-1 axis
Metabolic Management
Ameliorates immunosuppression and improves diabetic kidney disease
Emotional Management
Alleviating emotional disorders such as anxiety, depression and insomnia
AKK PROBIO WIKI
AKK PROBIO (Akkermansia mucilaginosa) ranks among the most sought-after strains in gut microbiome research over the past decade. Though not naturally present in all human hosts, it exhibits strong associations with metabolic health and immune balance. Its unique capacity to degrade intestinal mucins and engage in intimate interactions with the host alone has ignited a global research fervour.
Learn MoreThe Superiority of AKK PROBIO™
Clinically Studied Strain
13 peer-reviewed publications and 7 clinical studies, including an 8-week randomized controlled trial.
Patented Technology
Backed by 18 granted domestic and international invention patents.
U.S. Regulatory Position
Dual self-affirmed GRAS; NDI 1468 completed for the pasteurized form.
